"Instruction" of God is a symbol of Divine Wisdom revealed in the Word of the Holy Scriptures, expressed in His Will, in His Laws, Commandments, transmitted to the peoples by the Servants of God - Patriarchs, Prophets, Jesus Christ, Apostles and all the Righteous.
"Instruction" of man is the transmission of righteous life experience, evangelizing the knowledge and fulfillment of God's Commandments, as well as warning man about the consequences of rejection, violation, perversion of God's Commandments.